1,4-dihydro-4-[3-[[[[3-[4-(3-methoxyphenyl)-1-piperidinyl]propyl]amino]carbonyl]amino]phenyl]-2,6-dimethyl-3,5-dimethyl ester-3,5-pyridinedicarboxylic acid
1,4-Dihydro-4-[3-[[[[3-[4-(3-methoxyphenyl)-1-piperidinyl]propyl]amino]carbonyl]amino]phenyl]-2,6-dimethyl-3,5-pyridinedicarboxylicacid3,5-dimethylesterL-Lactate
CAS: 186185-03-5
Molecular Formula: C33H42N4O6
1,4-dihydro-4-[3-[[[[3-[4-(3-methoxyphenyl)-1-piperidinyl]propyl]amino]carbonyl]amino]phenyl]-2,6-dimethyl-3,5-dimethyl ester-3,5-pyridinedicarboxylic acid - Names and Identifiers
1,4-dihydro-4-[3-[[[[3-[4-(3-methoxyphenyl)-1-piperidinyl]propyl]amino]carbonyl]amino]phenyl]-2,6-dimethyl-3,5-dimethyl ester-3,5-pyridinedicarboxylic acid - Physico-chemical Properties
| Molecular Formula | C33H42N4O6 |
| Molar Mass | 590.71 |
| Density | 1.188±0.06 g/cm3(Predicted) |
| Boling Point | 707.5±60.0 °C(Predicted) |
| Solubility | DMSO: >10mg/mL |
| Appearance | powder |
| Color | light yellow to yellow |
| pKa | 13.94±0.46(Predicted) |
| Storage Condition | Desiccate at +4°C |
1,4-dihydro-4-[3-[[[[3-[4-(3-methoxyphenyl)-1-piperidinyl]propyl]amino]carbonyl]amino]phenyl]-2,6-dimethyl-3,5-dimethyl ester-3,5-pyridinedicarboxylic acid - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| WGK Germany | 3 |
1,4-dihydro-4-[3-[[[[3-[4-(3-methoxyphenyl)-1-piperidinyl]propyl]amino]carbonyl]amino]phenyl]-2,6-dimethyl-3,5-dimethyl ester-3,5-pyridinedicarboxylic acid - References
| biological activity | BMS-193885 is a potent, selective, competitive and brain-permeable Neuropeptide Y1 receptor antagonist, the Ki is 3.3 nM and The IC50 value for hY1 is 5.9 nM. The selectivity is 100 times higher than that of α1 receptor and 160 times higher than that of hY2, hY4 and hY5 receptors. |
| Target | Ki: 3.3 nM (Neuropeptide Y 1 receptor) IC50: 5.9 nM (hY 1 ) |
Last Update：2024-04-09 20:49:11
![1,4-dihydro-4-[3-[[[[3-[4-(3-methoxyphenyl)-1-piperidinyl]propyl]amino]carbonyl]amino]phenyl]-2,6-dimethyl-3,5-dimethyl ester-3,5-pyridinedicarboxylic acid](http://res.chembk.com/assets/str/2d/1/18/186185-03-5.png)